Minoru Sakakibara Selected Research

N- (2- hydroxyethyl)- N,2- dimethyl- 8- ((5- methyl- 3,4- dihydro- 2H- chromen- 4- yl)amino)imidazo(1,2- a)pyridine- 6- carboxamide

2/2009

N-(2-hydroxyethyl)-N,2-dimethyl-8-{[(4R)-5-methyl-3,4-dihydro-2H-chromen-4-yl]amino}imidazo[1,2-a]pyridine-6-carboxamide (PF-03716556), a novel, potent, and selective acid pump antagonist for the treatment of gastroesophageal reflux disease.

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Minoru Sakakibara Research Topics

Disease

1	Motor Disorders 05/2009
1	Gastroesophageal Reflux (GERD) 02/2009
1	Toxic Optic Neuropathy 08/2005

Drug/Important Bio-Agent (IBA)

1	4- ((4- ((((3- Isopropyl- 2- oxo- 2,3- dihydro- 1H- benzimidazol- 1- yl)carbonyl)amino)methyl)piperidin- 1- yl)methyl)tetrahydro- 2H- pyran- 4- carboxylic acidIBA 05/2009
1	Proton Pump InhibitorsIBA 02/2009
1	N- (2- hydroxyethyl)- N,2- dimethyl- 8- ((5- methyl- 3,4- dihydro- 2H- chromen- 4- yl)amino)imidazo(1,2- a)pyridine- 6- carboxamideIBA 02/2009
1	Histamine (Histamine Dihydrochloride)FDA Link 02/2009
1	pyridineIBA 02/2009
1	AcidsIBA 02/2009
1	imidazoleIBA 08/2005
1	PyransIBA 08/2005
1	Arachidonate 5-Lipoxygenase (5 Lipoxygenase)IBA 08/2005

Therapy/Procedure

1	Therapeutics 02/2009